Modified Human

Modified Humans are that of Humans with magical powers known as Youjutsu (Monster Arts). This species have not been seen in Rosario+Vampire until Tsukune Aono, who was that of a mere human had his body reconstructed and was inserted with 109 needles that had threads of energy that sews and reconstruct cells which forms a channel that amplifies the energy which is the source of youjutsu inside his body by the dark lord, Touhou Fuhai, who developed the Human Modification Technique. When the technique was completed, Tsukune emerged as the very first Modified-Human.

Known Modified Human

Tsukune Aono (formerly)

Trivia

Tsukune become a Modified-Human not only to learn Youjutsu, but to have better control over his Vampiric powers.
Modified-Humans are also known as "Sorcerers". (English manga)